diff --git a/CMakeLists.txt b/CMakeLists.txt
index fdccd03027..99323807a9 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -115,8 +115,8 @@ set(CMAKE_RUNTIME_OUTPUT_DIRECTORY ${CMAKE_BINARY_DIR}/Binaries)
 if (WIN32)
   set(CMAKE_RUNTIME_OUTPUT_DIRECTORY ${CMAKE_SOURCE_DIR}/Binary)
 
-	if (CMAKE_SYSTEM_PROCESSOR STREQUAL "aarch64")
-	  string(APPEND CMAKE_RUNTIME_OUTPUT_DIRECTORY /ARM64)
+  if (CMAKE_SYSTEM_PROCESSOR STREQUAL "aarch64")
+    string(APPEND CMAKE_RUNTIME_OUTPUT_DIRECTORY /ARM64)
   endif()
 
   set(CMAKE_RUNTIME_OUTPUT_DIRECTORY_DEBUG ${CMAKE_RUNTIME_OUTPUT_DIRECTORY})
@@ -557,7 +557,12 @@ add_subdirectory(Externals/imgui)
 add_subdirectory(Externals/glslang)
 
 if(ENABLE_VULKAN)
-  add_definitions(-DUSE_VULKAN)
+  add_definitions(-DHAS_VULKAN)
+endif()
+
+if(NOT WIN32 OR (NOT (CMAKE_SYSTEM_PROCESSOR STREQUAL "aarch64")))
+  # OpenGL is available on all platforms except windows-arm64
+  add_definitions(-DHAS_OPENGL)
 endif()
 
 find_package(pugixml)
diff --git a/Source/Core/VideoCommon/VideoBackendBase.cpp b/Source/Core/VideoCommon/VideoBackendBase.cpp
index 690745f9c8..c4c26ed6a3 100644
--- a/Source/Core/VideoCommon/VideoBackendBase.cpp
+++ b/Source/Core/VideoCommon/VideoBackendBase.cpp
@@ -22,11 +22,6 @@
 #include "Core/ConfigManager.h"
 #include "Core/Core.h"
 
-// OpenGL is not available on Windows-on-ARM64
-#if !defined(_WIN32) || !defined(_M_ARM64)
-#define HAS_OPENGL 1
-#endif
-
 // TODO: ugly
 #ifdef _WIN32
 #include "VideoBackends/D3D/VideoBackend.h"
@@ -37,7 +32,9 @@
 #include "VideoBackends/OGL/VideoBackend.h"
 #include "VideoBackends/Software/VideoBackend.h"
 #endif
+#ifdef HAS_VULKAN
 #include "VideoBackends/Vulkan/VideoBackend.h"
+#endif
 
 #include "VideoCommon/AsyncRequests.h"
 #include "VideoCommon/BPStructs.h"
@@ -225,7 +222,7 @@ const std::vector<std::unique_ptr<VideoBackendBase>>& VideoBackendBase::GetAvail
     backends.push_back(std::make_unique<DX11::VideoBackend>());
     backends.push_back(std::make_unique<DX12::VideoBackend>());
 #endif
-#ifdef USE_VULKAN
+#ifdef HAS_VULKAN
     backends.push_back(std::make_unique<Vulkan::VideoBackend>());
 #endif
 #ifdef HAS_OPENGL
diff --git a/Source/Core/VideoCommon/VideoCommon.vcxproj b/Source/Core/VideoCommon/VideoCommon.vcxproj
index 53842ece7d..bd144ae0f6 100644
--- a/Source/Core/VideoCommon/VideoCommon.vcxproj
+++ b/Source/Core/VideoCommon/VideoCommon.vcxproj
@@ -15,6 +15,16 @@
     <Import Project="$(VSPropsDir)PCHUse.props" />
   </ImportGroup>
   <PropertyGroup Label="UserMacros" />
+  <ItemDefinitionGroup Condition="'$(Platform)'=='x64'">
+    <ClCompile>
+      <PreprocessorDefinitions>HAS_OPENGL;%(PreprocessorDefinitions)</PreprocessorDefinitions>
+    </ClCompile>
+  </ItemDefinitionGroup>
+  <ItemDefinitionGroup>
+    <ClCompile>
+      <PreprocessorDefinitions>HAS_VULKAN;%(PreprocessorDefinitions)</PreprocessorDefinitions>
+    </ClCompile>
+  </ItemDefinitionGroup>
   <ItemGroup>
     <ClCompile Include="AbstractFramebuffer.cpp" />
     <ClCompile Include="AbstractStagingTexture.cpp" />
@@ -191,4 +201,4 @@
   <Import Project="$(VCTargetsPath)\Microsoft.Cpp.targets" />
   <ImportGroup Label="ExtensionTargets">
   </ImportGroup>
-</Project>
+</Project>
\ No newline at end of file