diff --git a/Source/Core/Core/IOS/USB/USB_VEN/VEN.cpp b/Source/Core/Core/IOS/USB/USB_VEN/VEN.cpp
index 4bb28968e3..e969417839 100644
--- a/Source/Core/Core/IOS/USB/USB_VEN/VEN.cpp
+++ b/Source/Core/Core/IOS/USB/USB_VEN/VEN.cpp
@@ -105,7 +105,9 @@ s32 USB_VEN::SubmitTransfer(USB::Device& device, const IOCtlVRequest& ioctlv)
 IPCCommandResult USB_VEN::CancelEndpoint(USBV5Device& device, const IOCtlRequest& request)
 {
   const u8 endpoint = static_cast<u8>(Memory::Read_U32(request.buffer_in + 8));
-  GetDeviceById(device.host_id)->CancelTransfer(endpoint);
+  // IPC_EINVAL (-4) is returned when no transfer was cancelled.
+  if (GetDeviceById(device.host_id)->CancelTransfer(endpoint) < 0)
+    return GetDefaultReply(IPC_EINVAL);
   return GetDefaultReply(IPC_SUCCESS);
 }