diff --git a/Source/Core/Core/HLE/HLE.cpp b/Source/Core/Core/HLE/HLE.cpp
index a598e8d2b0..9c9471434d 100644
--- a/Source/Core/Core/HLE/HLE.cpp
+++ b/Source/Core/Core/HLE/HLE.cpp
@@ -76,6 +76,14 @@ void Patch(u32 addr, std::string_view func_name)
 
 void PatchFixedFunctions()
 {
+  // MIOS puts patch data in low MEM1 (0x1800-0x3000) for its own use.
+  // Overwriting data in this range can cause the IPL to crash when launching games
+  // that get patched by MIOS. See https://bugs.dolphin-emu.org/issues/11952 for more info.
+  // Not applying the Gecko HLE patches means that Gecko codes will not work under MIOS,
+  // but this is better than the alternative of having specific games crash.
+  if (SConfig::GetInstance().m_is_mios)
+    return;
+
   // HLE jump to loader (homebrew).  Disabled when Gecko is active as it interferes with the code
   // handler
   if (!SConfig::GetInstance().bEnableCheats)
diff --git a/Source/Core/Core/IOS/MIOS.cpp b/Source/Core/Core/IOS/MIOS.cpp
index 3be52ed411..7a4ce4a6bc 100644
--- a/Source/Core/Core/IOS/MIOS.cpp
+++ b/Source/Core/Core/IOS/MIOS.cpp
@@ -86,6 +86,7 @@ bool Load()
   NOTICE_LOG_FMT(IOS, "IPL ready.");
   SConfig::GetInstance().m_is_mios = true;
   DVDInterface::UpdateRunningGameMetadata();
+  SConfig::OnNewTitleLoad();
   return true;
 }
 }  // namespace IOS::HLE::MIOS